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Current and future status of JAK inhibitors

Conditions including leaky gut, celiac disease, inflammatory bowel disease, or simply a poor diet or chronic stress can contribute to micronutrient deficiencies

Complex I inhibitors, such as IACS-010759 and BAY87-2243, have demonstrated potent efficacy in preclinical models of CRC subtypes with high OXPHOS dependence [143]

This is due to its many health benefits, including its anti-inflammatory, antioxidant, and possibly modulating effects on oestrogen hormone receptor signalling or the stimulation of DNA repair pathways

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